Coastal regions support biodiversity and livelihoods but face growing climate-related threats. Our research focuses on the Akplabanya Indigenous community in Ghana, examining human-environment interactions and adaptation responses within a social-ecological systems (SES) framework. Through fieldwork involving interviews, observations, and discussions, we identified key challenges such as climate change, resource shifts, biodiversity loss, pollution, and population changes. Community responses include fostering a sense of place, collective action, knowledge adaptation, and institutional partnerships. Our findings highlight the need for targeted policy interventions to support Indigenous resilience, providing insights for scientists, policymakers, and researchers addressing coastal sustainability.